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Weight loss techniques: Today everyone wants to keep the body healthy. There is also a risk of many diseases due to weight gain. To lose weight, one should control eating habits, change lifestyle and do as much light exercise as possible. But if you are taking any medicine to lose weight, then be careful. A new US study has shown that Wegovy and Ozempic, taken for rapid weight loss, can pose a risk of serious side effects. This can also cause stomach paralysis. Stomach paralysis requires frequent emptying of the stomach. Stomach paralysis can cause sudden weight loss, malnutrition and other complications and may also require surgery for treatment.
Big revelation in an American study
The study said that people who use Wegovy and Ozempic, known as GLP-1 agonist drugs, to lose weight may have a 30% increased risk of stomach paralysis in people who take these drugs. People who took this drug Glucagon-like peptide-1 receptor agonists (GLP-1RAs), also known as GLP-1 agonists, are a class of drugs used to treat type-2 diabetes and obesity.
The report, presented at the medical conference Digestive Diseases Week 2024 in Washington on Saturday, is based on an analysis of records of over three lakh people with diabetes and obesity, of whom 1.65 lakh were prescribed GLP-1 agonists. It also slows down the emptying of the stomach and is known to stimulate insulin production.
Be careful if you are taking medicines
Dr. Prateek Sharma, a professor of medicine at Kansas University, said that the side effects of this drug pose a serious risk of stomach paralysis, but given the high use of GLP-1 drugs or weight loss drugs, it is very important to warn people about it. Apart from this, 'These drugs are new, although they have been positively effective, we are still studying their long-term side effects. So I think people who are taking this drug need to be very careful.'
These medicines are available secretly in India
Wegovy and Ozempic are not legally available in India. However, according to reports, many people also buy these drugs from the grey market at a high price. Recently, Danish company Novo Nordisk has launched 'Rybelsus' in tablet form in India, which contains semaglutide, the main ingredient of Ozempic. It is approved for diabetes management, but doctors say that this drug is also being used 'off-label' for weight loss.
Wegovy and Ozempic were also initially approved for diabetes. But a report that surfaced said that the drug could help in 10-15% weight loss in a year. So the US FDA approved its restricted use in people with severe disease as well. Soon the drug group created a stir across the world, as some of the biggest celebrities including Elon Musk and Oprah Winfrey said, “We are using it.”
Learn what Wegovy and Ozempic do
According to Dr Randhir Sood, drugs like Wegovy and Ozempic start their action by slowing down the movement of the stomach. Thus appetite is reduced. And when one starts taking this drug, he experiences nausea and vomiting, but in some cases these side effects were also mild. He said. I have not seen any case of stomach paralysis yet, but these are early days of its use in India.
Health records of more than 12 crore patients were analyzed
In this US study, Sharma and his colleagues used a large database to analyse the health records of more than 12 million patients, focusing on people with diabetes and obesity. They compared patients taking GLP-1 drugs to a control group in which they obtained the same demographic and health factors. After a year, they found that 32% of GLP-1 users experienced gastrointestinal problems such as nausea, GERD and stomach cramps.
That is, while GLP-1 users underwent more GI-related procedures, they had fewer ER visits and hospital admissions. That is, while GLP-1 drugs increase GI side effects, they do not cause serious health problems that require emergency care or hospitalization.
Talking about this, a professor from Kansas University said, 'We are not saying that it should not be used. But our research clearly shows that gastrointestinal side effects, such as stomach paralysis, which can impair healthy life, require more monitoring.'