Early detection of sepsis: Canadian researchers in their study have reported a non-invasive method for early detection of sepsis. Sepsis is an uncommon infection, which, if delayed in treatment, can cause many parts of the body to stop functioning. Often such deadly infections are detected late, due to which millions of people die every year around the world.
How to Diagnose Sepsis?
Researchers at Western University in Ontario, Canada have shown that non-invasive imaging tests that measure blood flow in bone muscles are effective in detecting sepsis infection.
“The study shows that the brain is partially protected in early sepsis, but the disease can be identified by detecting changes in the microhemodynamics of skeletal muscle,” the research team said in a paper published in the journal The FASEB. Is.’
Now how is the treatment done?
Currently, sepsis is initially treated with antibiotics and vasopressors. These medicines help control infection and systemic hypotension (low blood pressure) and are helpful in increasing survival rates. However, currently, there is a lack of tools that can detect sepsis in its early stages. Thus, there is a global need for affordable and accessible technology for early detection and treatment of sepsis, the team said.
In the study, the team used imaging techniques called hyperspectral near-infrared spectroscopy and diffuse correlation spectroscopy, which are commonly used to monitor the condition of the tissues of bed-ridden patients.
How effective is this test?
To see how effective the imaging technique was, the team experimented with mice. With the help of imaging techniques, it became possible to identify signs of sepsis in the microcirculation of bone muscles. “Sepsis is a leading cause of death worldwide, disproportionately affecting vulnerable populations and those with fewer resources,” said co-author Rasa Eskandari, a doctoral student at Western University.
“Because early detection can significantly improve outcomes and save lives,” Eskandari said. Therefore, our team is working on developing simple techniques for early detection of sepsis and timely intervention.”