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The research has been published in the journal Annals of Medicine and explores how insulin resistance may increase the risk of aortic stenosis which leads to heart attacks. This study may open new avenues for treating and reducing the risk of heart disease.
heart disease from insulin resistance
In this research, researchers from Kuopio University Hospital in Finland analyzed data from 10,144 men aged 45 to 73 years and found that men who had higher insulin resistance had a higher risk of developing aortic stenosis. This condition occurs when the arteries that supply blood from the heart to the body start narrowing.
Biomarker Identification
Researchers identified several biomarkers related to insulin resistance in people affected with aortic stenosis, including fasting insulin, proinsulin, and serum C-peptide. These biomarkers served as important predictors of aortic stenosis, and this study made it clear that insulin resistance may be an important risk factor for aortic stenosis.
health management essential
“This new finding highlights insulin resistance as an important risk factor for aortic stenosis,” said Dr. Johanna Kuusisto, lead author of the research.
Study findings
The study found 116 men with aortic stenosis after a mean follow-up period of 10.8 years. The results showed that insulin sensitivity can be improved by weight loss and regular exercise, which may help reduce disease risk. Dr. Kuchisto has expressed the need for more studies based on this research so that effective measures can be found to avoid heart disease and other related health problems.